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an erection that will not disappear (priapism). Should you have an erection that lasts a lot more than 4 hrs, get medical enable straight away. If It's not taken care of straight away, priapism can completely hurt your penis.Il tadalafil può inibire debolmente anche la fosfodiesterasi di tipo 6 (PDE6; 700 volte meno potente sulla PDE6 rispetto all